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850542P

Avanti

MEGA-10

Avanti Polar Lipids 850542P, powder

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Synonym(s):
N-decanoyl-N-methylglucamine
Empirical Formula (Hill Notation):
C17H35NO6
CAS Number:
Molecular Weight:
349.46
UNSPSC Code:
12161902
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

mol wt

349.46 g/mol

packaging

pkg of 1 × 1 g (850542P-1g)

manufacturer/tradename

Avanti Polar Lipids 850542P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O

InChI

1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3/t13-,14+,16+,17+/m0/s1

InChI key

UMWKZHPREXJQGR-XOSAIJSUSA-N

General description

Acyl-N-methylglucamide (MEGA) detergents are non-ionic detergents that provide a good starting point for your structural biology work. The hydrophilic head groups offer ample strength to extract proteins while still providing the capability to stabilize proteins in solution and promote crystal growth.
MEGA-10/N-decanoyl-N-methylglucamine is a longer carbon chain or a sugar-based surfactant. It is a member of the fatty acid glucamides family.

Packaging

20 mL Clear Glass Screw Cap Vial (850542P-1g)

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Influence of N-octanoyl-N-methylglucamine and N-decanoyl-N-methylglucamine on the kinetics and mechanism of Zn2+ ions electroreduction
Nieszporek J and Dagci K
Electrochimica Acta, 125, 473-481 (2014)
Light scattering and fluorescence studies of non-ionic surfactant binary mixtures formed by MEGA-10 and C12E8
Molina-Bolivar JA and Ruiz CC
Journal of Molecular Liquids, 155(2-3), 96-102 (2010)
Matthew A Churchward et al.
Proteome science, 3(1), 5-5 (2005-06-09)
The analysis of hydrophobic membrane proteins by two-dimensional gel electrophoresis has long been hampered by the concept of inherent difficulty due to solubility issues. We have optimized extraction protocols by varying the detergent composition of the solubilization buffer with a
Jen-Hua Chuang et al.
Analytical biochemistry, 418(2), 298-300 (2011-08-30)
We studied the extraction and analysis of integral membrane proteins possessing hydrophobic and hydrophilic domains and found that a nonionic detergent called MEGA-10, used in lysis buffers, had a superior extraction effect compared to most conventional detergents. A sodium dodecyl
J M Hierrezuelo et al.
Langmuir : the ACS journal of surfaces and colloids, 20(24), 10419-10426 (2004-11-17)
The mixed micellization between the nonionic surfactant decanoyl-N-methylglucamide (MEGA-10) and the common sodium dodecyl sulfate (SDS) in aqueous solutions of 0.1 M NaCl was investigated by the fluorescence probe method. The critical micelle concentrations were determined by the pyrene 1:3

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