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Key Documents

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Safety Information

W421501

Sigma-Aldrich

Tyramine

98%, FG

Synonym(s):

2-(4-Hydroxyphenyl)ethylamine, 4-(2-Aminoethyl)phenol, 4-Hydroxyphenethylamine

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25 μL
CN¥2,257.75
100 μL
CN¥4,582.18
200 μL
CN¥5,503.01

CN¥2,257.75

Available to ship onApril 27, 2025Details

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25 μL
CN¥2,257.75
100 μL
CN¥4,582.18
200 μL
CN¥5,503.01

About This Item

Linear Formula:
HOC6H4CH2CH2NH2
CAS Number:
51-67-2
Molecular Weight:
137.18
FEMA Number:
4215
Beilstein:
1099914
EC Number:
200-115-8
MDL number:
MFCD00008193
UNSPSC Code:
12164502
PubChem Substance ID:
329830683
Flavis number:
11.007
NACRES:
NA.21
grade:
FG
biological source:
synthetic
food allergen:
no known allergens

CN¥2,257.75

Available to ship onApril 27, 2025Details

Request a Bulk OrderRequest more information

biological source

synthetic

Quality Level

400

grade

FG

reg. compliance

EU Regulation 1334/2008 & 872/2012
FDA 21 CFR 110

Assay

98%

bp

175-181 °C/8 mmHg (lit.)

mp

160-162 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

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This Item
P6623P1869P5872
Anti-Phosphoserine antibody, Mouse Monoclonal clone PSR-45, purified from hybridoma cell culture

P5747

Anti-Phosphoserine antibody, Mouse Monoclonal

Anti-Phosphothreonine antibody, Mouse monoclonal clone PTR-8, purified from hybridoma cell culture

P6623

Anti-Phosphothreonine antibody, Mouse monoclonal

Anti-Phosphotyrosine antibody, Mouse monoclonal clone pT-154, purified from hybridoma cell culture

P1869

Anti-Phosphotyrosine antibody, Mouse monoclonal

Anti-Phosphotyrosine antibody, Mouse monoclonal clone PT-66, purified from hybridoma cell culture

P5872

Anti-Phosphotyrosine antibody, Mouse monoclonal

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

-

biological source

mouse

clone

PSR-45, monoclonal

clone

PTR-8, monoclonal

clone

pT-154, monoclonal

clone

PT-66, monoclonal

technique(s)

dot blot: suitable, microarray: suitable, indirect ELISA: 0.3-0.6 μg/mL using phosphoserine conjugated to BSA, western blot: 2.5-5.0 μg/mL using total rat brain extract.

technique(s)

dot blot: suitable, immunocytochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: 0.5-1 μg/mL, microarray: suitable, western blot: 5-10 μg/mL using A431 cell extracts

technique(s)

direct ELISA: suitable, immunohistochemistry: suitable, microarray: suitable, western blot: 2-4 μg/mL using total extract of A431 cells stimulated by EGF

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: 0.5-1.0 μg/mL using phosphotyrosine conjugated to BSA, radioimmunoassay: suitable, western blot: 0.25-0.5 μg/mL using total cell extract of human platelets

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Biochem/physiol Actions

Can enter catecholaminergic terminals and be released as a false transmitter.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
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    Certificates of Analysis (COA)

    Lot/Batch Number
    SHBQ0619
    SHBP7807
    SHBP8983
    SHBN7388
    SHBN5574

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    Stephan A Chalon et al.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 28(9), 1685-1693 (2003-06-05)
    Evidence suggests that compounds that increase the synaptic availability of more than one neurotransmitter have greater efficacy in the treatment of depression than single-acting drugs. Preclinical studies indicate that duloxetine acts to inhibit serotonin (5-HT) and norepinephrine (NE) transporters. The
    Thomas Roeder
    Annual review of entomology, 50, 447-477 (2004-09-10)
    Octopamine (OA) and tyramine (TA) are the invertebrate counterparts of the vertebrate adrenergic transmitters. They are decarboxylation products of the amino acid tyrosine, with TA as the biological precursor of OA. Nevertheless, both compounds are independent neurotransmitters that act through
    Adam B Braunschweig et al.
    Nano letters, 7(7), 2030-2036 (2007-06-15)
    Tyrosinase activity is monitored by pi-donor-acceptor force interactions between a bipyridinium-modified AFM tip and the biocatalytic reaction product generated on a tyramine- (or dopamine-) modified surface. Upon oxidation of the surface to dopaquinone as a result of tyrosinase activity, force
    D R Varma et al.
    The Journal of pharmacology and experimental therapeutics, 265(3), 1096-1104 (1993-06-01)
    At concentrations higher than that required to produce maximal vasoconstriction, tyramine caused concentration-dependent relaxation of rat aortic strips contracted maximally by tyramine, norepinephrine, phenylephrine, 5-hydroxytryptamine, prostaglandin F2 alpha, endothelin, angiotensin II and potassium; isoproterenol did not relax potassium-contracted strips. The
    Moussa B H Youdim et al.
    Neurotoxicology, 25(1-2), 243-250 (2003-12-31)
    The major side effect with the use of first generation of non selective monoamine oxidase (MAO) inhibitors as neuropsychiatric drugs was what became known as the "cheese reaction". Namely, potentiation of sympathomimetic activity of ingested tyramine present in cheese and
    View All Related Papers

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