All Photos(1)
Synonym(s):
2,5-Dioxo-1-pyrrolidinyl 29-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-9,25-dioxo-12,15,18,21-tetraoxa-4,5-dithia-8,24-diazanonacosanoate, Polyethylene glycol
Empirical Formula (Hill Notation):
C30H49N5O11S3
CAS Number:
Molecular Weight:
751.93
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
>90%
form
solid or viscous liquid
reaction suitability
reaction type: Biotinylations
reagent type: cross-linking reagent
functional group
disulfide
polymer architecture
shape: linear
functionality: monofunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(NCCSSCCC(ON1C(CCC1=O)=O)=O)CCOCCOCCOCCOCCNC(CCCCC2C3NC(NC3CS2)=O)=O
Related Categories
Features and Benefits
NHS-S-S-dPEG®4-biotin is used extensively to label molecules that contain a free amine with biotin. This dPEG® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin. NHS-S-S-dPEG®4-biotin contains a disulfide group in the linear chain, allowing the biotin to be cleaved reductively from the labeled molecule.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
related product
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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