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M86685

Sigma-Aldrich

α-Methyltryptamine

99%

Synonym(s):

3-(2-Aminopropyl)indole

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About This Item

Empirical Formula (Hill Notation):
C11H14N2
CAS Number:
Molecular Weight:
174.24
EC Number:
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:

Quality Level

Assay

99%

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

98-100 °C (lit.)

SMILES string

CC(N)Cc1c[nH]c2ccccc12

InChI

1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3

InChI key

QSQQQURBVYWZKJ-UHFFFAOYSA-N

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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I S Severina
Biochemistry international, 9(2), 219-228 (1984-08-01)
A new hitherto unknown important property of D-amphetamine (but not L-isomer) and DL-alpha-N-methyltryptamine was discovered. These substances decrease the irreversible inhibition by clorgyline of tyramine deamination without affecting a sharply expressed inhibitory effect of clorgyline on serotonin oxidation. As a
T Kanamori et al.
Xenobiotica; the fate of foreign compounds in biological systems, 38(12), 1476-1486 (2008-11-05)
1. The in vivo metabolism of alpha-methyltryptamine (AMT), a psychoactive tryptamine analogue, was studied in rats. 2. Male Wistar rats were administered 10 mg kg(-1) AMT orally and 24-h urine fractions were collected. After enzymatic hydrolysis of the urine sample
Involvement of 5-hydroxytryptamine and dopamine neurones in the behavioural effects of alpha-methylytryptamine.
C A Marsden
Neuropharmacology, 19(8), 691-698 (1980-08-01)
A S Barer et al.
Kosmicheskaia biologiia i aviakosmicheskaia meditsina, 22(6), 66-73 (1988-11-01)
The effect of pharmacological stimulants and prescriptions on the thermal status of man and their possible use to extend the exposure to the cold environment were investigated. The effectiveness of the following drugs and prescriptions was assessed: sydnocarb, phenamine, indopan;
H Scheinin et al.
Pharmacology & toxicology, 61(3), 167-171 (1987-09-01)
The kinetics of monoamine metabolites, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA), in cisternal CSF were determined after monoamine oxidase (MAO) inhibition (pargyline, 100 mg/kg) and tyrosine hydroxylase inhibition (alpha-methyl-p-tyrosine, alpha-MPT, 250 mg/kg) in awake rats. In addition

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