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Merck
CN

M86685

α-Methyltryptamine

99%

Synonym(s):

3-(2-Aminopropyl)indole

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About This Item

Empirical Formula (Hill Notation):
C11H14N2
CAS Number:
299-26-3
Molecular Weight:
174.24
UNSPSC Code:
12352116
PubChem Substance ID:
329818066
EC Number:
206-073-7
MDL number:
MFCD00005654
Assay:
99%
Form:
solid

Key Documents

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InChI key

QSQQQURBVYWZKJ-UHFFFAOYSA-N

InChI

1S/C11H14N2/c1-8(12)6-9-7-13-11-5-3-2-4-10(9)11/h2-5,7-8,13H,6,12H2,1H3

SMILES string

CC(N)Cc1c[nH]c2ccccc12

assay

99%

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada; Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

Quality Level

100

mp

98-100 °C (lit.)

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
11120AZ
09422AZ
01827MR
16214TN
09611PF

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S Benkirane et al.
European journal of pharmacology, 131(2-3), 189-198 (1986-11-19)
In slices of the rat hippocampus, alpha 2-adrenoceptors located presynaptically on serotonergic nerve terminals modulate the electrically evoked calcium-dependent release of [3H]serotonin [( 3H]5HT). We have investigated the effects of a naturally occurring trace amine, beta-phenylethylamine (beta-PEA), on noradrenergic transmission
Involvement of 5-hydroxytryptamine and dopamine neurones in the behavioural effects of alpha-methylytryptamine.
C A Marsden
Neuropharmacology, 19(8), 691-698 (1980-08-01)
Reevaluation of the products of tryptamine catalyzed by rabbit liver N-methyltransferases.
P A Crooks et al.
Biochemical pharmacology, 35(9), 1600-1603 (1986-05-01)
T Kanamori et al.
Xenobiotica; the fate of foreign compounds in biological systems, 38(12), 1476-1486 (2008-11-05)
1. The in vivo metabolism of alpha-methyltryptamine (AMT), a psychoactive tryptamine analogue, was studied in rats. 2. Male Wistar rats were administered 10 mg kg(-1) AMT orally and 24-h urine fractions were collected. After enzymatic hydrolysis of the urine sample
H Scheinin et al.
Pharmacology & toxicology, 61(3), 167-171 (1987-09-01)
The kinetics of monoamine metabolites, 3-methoxy-4-hydroxyphenylglycol (MHPG), 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA), in cisternal CSF were determined after monoamine oxidase (MAO) inhibition (pargyline, 100 mg/kg) and tyrosine hydroxylase inhibition (alpha-methyl-p-tyrosine, alpha-MPT, 250 mg/kg) in awake rats. In addition
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