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904996

Sigma-Aldrich

Conjugated Polymer Nanoparticles incorporating iron oxide

fluorescence λem 680 nm, 100 μg/mL in H2O

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Synonym(s):
Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles
UNSPSC Code:
12162002
NACRES:
NA.23

form

nanoparticles

concentration

100 μg/mL in H2O

fluorescence

λem 680 nm

storage temp.

2-8°C

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Application

Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
  • Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
  • Immunohistochemistry and Immunocytochemistry
  • Flow Cytometry
  • Rapid Diagnostic Tests (RDTs)
  • Tissue Imaging
  • 2-Photon Imaging
  • NIR Imaging

Storage and Stability

The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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General synthesis of high-performing magneto-conjugated polymer core-shell nanoparticles for multifunctional theranostics
Yan H, et al.
Nano Research, 10(2), 704-717 (2017)
General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics
H Yan et al.
Nano Research, 10, 704-704 (2017)
Loading Graphene Quantum Dots into Optical-Magneto Nanoparticles for Real-Time Tracking In Vivo
Wang Y, et al.
Materials, 12(13), 2191-2191 (2019)
Fluorescent magnetic nanoparticles for biomedical applications
Chekina N, et al.
Journal of Materials Chemistry, 21(21), 7630-7639 (2011)
Philip Howes et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010-06-25)
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers

Articles

Iron Oxide Conjugated Polymer Nanoparticles

Iron oxide incorporated CPNs offer high brightness for fluorescence and MRI applications, encapsulated in biocompatible surfactant.

Applications of Iron Oxide Incorporated Conjugated Polymer Nanoparticles

CPNs offer sensitivity and stability, aiding various assays; may enable rapid diagnostic tests for healthcare needs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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