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Merck
CN

900957

Azide agarose

Synonym(s):

Azide functionalized agarose

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About This Item

NACRES:
NA.22
UNSPSC Code:
12352125
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form

slurry (50% slurry in 20% ethanol / 80% water)

reaction suitability

reaction type: click chemistry

refractive index

n/D 1.343

density

0.978 g/mL

storage temp.

2-8°C

Quality Level

Application

Azide agarose is a 6% crosslinked agarose resin that is activated with azide functional groups for covalent capture of alkyne-tagged biomolecules via copper(I)-catalyzed alkyne-azide or copper(I)-free strain-promoted alkyne-azide click chemistry approach. This product can be used for either a batch protocol or a low-pressure column method.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Sreenivas Punna et al.
Bioconjugate chemistry, 16(6), 1536-1541 (2005-11-17)
Successful purification of biological molecules by affinity chromatography requires the attachment of desired ligands to biocompatible chromatographic supports. The Cu(I)-catalyzed cycloaddition of azides and alkynes-the premier example of "click chemistry"-is an efficient way to make covalent connections among diverse molecules
?Clickable? agarose for affinity chromatography.
Punna S, et al.
Bioconjugate Chemistry, 16(6), 1536-1541 (2005)

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