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Merck
CN

900331

VPhos

95%, solid

Synonym(s):

2-Dicyclohexylphosphino-2′-methoxy-4′,6′-di-tert-butylbiphenyl, 4,6-Di-tert-butyl-2′-dicyclohexylphosphino-2-methoxybiphenyl

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About This Item

Empirical Formula (Hill Notation):
C33H49OP
CAS Number:
Molecular Weight:
492.72
UNSPSC Code:
12161600
NACRES:
NA.22
MDL number:
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Product Name

VPhos, 95%

SMILES string

P(C4CCCCC4)(C3CCCCC3)c1c(cccc1)c2c(cc(cc2C(C)(C)C)C(C)(C)C)OC

InChI

1S/C33H49OP/c1-32(2,3)24-22-28(33(4,5)6)31(29(23-24)34-7)27-20-14-15-21-30(27)35(25-16-10-8-11-17-25)26-18-12-9-13-19-26/h14-15,20-23,25-26H,8-13,16-19H2,1-7H3

InChI key

LYVFKWGKMKCNPE-UHFFFAOYSA-N

assay

95%

form

solid

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: catalyst
reaction type: Cross Couplings

reagent type: ligand
reaction type: click chemistry

mp

113-118 °C

functional group

phosphine

Quality Level

Application

As the Pd G4 complex, this ligand from the Buchwald group offers best-in-class performance in the micellar aqueous Negishi coupling of heterocyclic alkyl bromides.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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