793248
Polyhydroxylated fullerenes, water soluble
Synonym(s):
C60(OH)n, water soluble C60, Fullerenols, Polyhydroxy fullerenes
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About This Item
Empirical Formula (Hill Notation):
C60(OH)n · mH2O (n>40, m>8)
NACRES:
NA.23
UNSPSC Code:
12352103
form
solid
color
light yellow to yellow
solubility
water: soluble >50 mg/mL, DMSO: slightly soluble, methanol: slightly soluble
storage temp.
2-8°C
Quality Level
Related Categories
General description
Polyhydroxylated fullerenes, (water soluble)(PHF) is a functionalized fullerene that is also called fullerenol which can be used as a molecular anti-oxidant and a nanoparticle. It is a non-toxic fullerene which is attached with 12-42 hydroxyl groups per molecule that result in water solubility. Its structure and the position of the hydroxyl groups will depend on the existing pH of the media.
Application
PHF may be incorporated in titanium dioxide to form a nanocomposite which can be potentially used in the photocatalysis of semiconductors. Its photothermal and therapeutic properties may be used in non-invasive image based therapy of cancer.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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Enhancement of nano titanium dioxide photocatalysis in transparent coatings by polyhydroxy fullerene.
Bai W, et al.
Applied Catalysis. B, Environmental, 125(1), 128-135 (2012)
Polyhydroxy fullerenes (fullerols or fullerenols): beneficial effects on growth and lifespan in diverse biological models.
Gao J, et al.
PLoS ONE, 6(5), e19976-e19976 (2011)
Yasukazu Saitoh et al.
Molecular and cellular biochemistry, 366(1-2), 191-200 (2012-04-03)
Reactive oxygen species has been suggested to be one of the key factors associated with the development of obesity. During spontaneous differentiation of mouse stromal preadipocytes OP9 into adipocytes, intracellular superoxide anion radicals (O (2) (-.) ) level markedly increases
Ken Kokubo et al.
ACS nano, 2(2), 327-333 (2009-02-12)
Using a novel hydrogen peroxide heating method, we synthesized milky white, water-soluble polyhydroxylated fullerenes (fullerenols) with 36-40 hydroxyl groups (estimated average) along with 8-9 secondary bound water molecules. The fullerenols exhibited high water solubility up to 58.9 mg/mL in a
Polyhydroxy fullerenes.
Georgieva AT, et al.
Journal of Nanoparticle Research, 15(7), 1690-1690 (2013)
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