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757799

Sigma-Aldrich

Poly(ethylene glycol) (N-hydroxysuccinimide 5-pentanoate) ether 2-(biotinylamino)ethane

average Mn 3,800, cross-linking reagent amine reactive, NHS ester, biotin

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Synonym(s):
Polyethylene glycol, Biotin polyoxyethylene maleimide, Biotin-PEG, Biotin-PEG maleimide, Biotinylated PEG, NHS - protected acid PEG, Poly(ethylene glycol) (N-hydroxysuccinimide acetic acid) ether biotin, biotin carboxylic acid PEG, protected valeric acid
Linear Formula:
C10H16N3O2S(C2H4O)nC8H8NO5
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

Quality Level

100

mol wt

PEG average Mn 3,400 (n ~ 77)
average Mn 3,800

reaction suitability

reagent type: cross-linking reagent
reactivity: amine reactive

mp

45-53 °C

Ω-end

NHS ester

α-end

biotin

polymer architecture

shape: linear
functionality: heterobifunctional

storage temp.

−20°C

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General description

Poly(ethylene glycol) (N-hydroxysuccinimide 5-pentanoate) ether 2-(biotinylamino)ethane is a heterobifunctional poly(ethylene glycol) (PEG) derivative with a biotin terminus.

Application

bioconjugation, drug delivery, PEG hydrogel, crosslinker, surface functionalization

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio) propionyl marker on the second terminus.
Kaiser K, et al.
Bioconjugate Chemistry, 8(4), 545-551 (1997)

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