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Sigma-Aldrich

Poly(ethylene glycol) diacrylate

average Mn 1,000, acrylate, MEHQ as inhibitor (may contain)

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Synonym(s):
Polyethylene glycol, PEG diacrylate
CAS Number:
26570-48-9
MDL number:
MFCD00081876
UNSPSC Code:
12162002
NACRES:
NA.23

form

solid

Quality Level

100

mol wt

average Mn 1,000

contains

MEHQ as inhibitor
≤1,500 ppm MEHQ as inhibitor (may contain)

composition

C2H3C(O)(OC2H4)nOC(O)C2H3

reaction suitability

reagent type: cross-linking reagent
reaction type: Polymerization Reactions

transition temp

Tm 32-37 °C

Mw/Mn

≤1.1

Ω-end

acrylate

α-end

acrylate

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

−20°C

SMILES string

OCCO.OC(=O)C=C

InChI

1S/C8H10O4/c1-3-7(9)11-5-6-12-8(10)4-2/h3-4H,1-2,5-6H2

InChI key

KUDUQBURMYMBIJ-UHFFFAOYSA-N

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General description

Poly(ethylene glycol) diacrylate (PEGDA) is a polyethylene glycol (PEG) based material that is used as a prepolymer solution that can be used in the formation of a cross-linked polymeric system.

Application

PEGDA has a wide range of usage potentially ranging from tissue engineering, photonics and other biological applications.

Preparation Note

Synthesized with an initial concentration of ≤1,500 ppm MEHQ

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H315,H317,H318

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Photoencapsulation of osteoblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering
Burdick JA and Anseth KS
Biomaterials, 23(22), 4315-4323 (2002)
Structural colour printing using a magnetically tunable and lithographically fixable photonic crystal
Kim H, et al.
Nature Photonics, 3(9), 534-534 (2009)
Preparation and characterization of crosslinked poly (ethylene glycol) diacrylate hydrogels as fouling-resistant membrane coating materials
Ju H, et al.
Journal of Membrane Science , 330(1-2), 180-188 (2009)
Release of protein from highly cross-linked hydrogels of poly (ethylene glycol) diacrylate fabricated by UV polymerization
Mellott MB, et al.
Biomaterials, 22(9), 929-941 (2001)

Articles

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

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