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Merck
CN

722332

Sigma-Aldrich

6-Amino-7-deazapurine

97%

Synonym(s):

4-Amino-7H-pyrrolo[2,3-d]pyrimidine

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2 L
CN¥3,207.82
4 X 4 L
CN¥16,804.89

CN¥3,207.82


Available to ship onApril 14, 2025Details


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2 L
CN¥3,207.82
4 X 4 L
CN¥16,804.89

About This Item

Empirical Formula (Hill Notation):
C6H6N4
CAS Number:
Molecular Weight:
134.14
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

CN¥3,207.82


Available to ship onApril 14, 2025Details


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Assay

97%

form

solid

mp

257-262 °C

SMILES string

Nc1ncnc2[nH]ccc12

InChI

1S/C6H6N4/c7-5-4-1-2-8-6(4)10-3-9-5/h1-3H,(H3,7,8,9,10)

InChI key

PEHVGBZKEYRQSX-UHFFFAOYSA-N

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1 of 4

This Item
12622575892B1375
assay

≥98.0%

assay

≥78.5%

assay

≥98.0% (dried material, NT)

assay

≥95%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

grade

ACS reagent, puriss. p.a.

grade

technical grade

grade

-

grade

-

mp

>300 °C (lit.)

mp

>300 °C (lit.)

mp

-

mp

300 °C (lit.)

impurities

8-10% water

impurities

-

impurities

~16% water

impurities

-

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Jennifer D Tibodeau et al.
Inorganic chemistry, 43(2), 408-410 (2004-01-21)
The effect of DNA bending on nucleobase electron transfer was investigated by studying the oxidation of double-stranded sequences containing seven repeats of the known bent sequence d(GGCA(1)A(2)A(3)A(4)A(5)A(6)C) where 7-deazaadenine (zA) was substituted at the A(3) position. Native gel electrophoresis was
Kiyohiko Kawai et al.
Nature chemistry, 1(2), 156-159 (2009-05-01)
Interest in using DNA as a building block for nanoelectronic sensors and devices stems from its efficient hole-conducting properties and the relative ease with which it can be organized into predictable nanometre-sized two- and three-dimensional structures. However, because a hole
A Ono et al.
Nucleic acids research, 12(23), 8939-8949 (1984-12-11)
Deoxydecanucleotides having a recognition sequence of Bgl II and Sau 3AI, and their 7-deazaadenine analogs were synthesized. The decanucleotides containing 7-deazaadenine in place of adenine were partially resistant to the hydrolysis by Sau 3AI and strongly resistant to that by
Akimitsu Okamoto et al.
Bioorganic & medicinal chemistry letters, 12(1), 97-99 (2001-12-12)
2-Amino-7-deazaadenine ((AD)A) was incorporated into oligodeoxynucleotides (ODN) and their base-pairing properties with natural nucleobases were investigated. In melting temperature (T(m)) experiments, the duplex containing an (AD)A/C base pair showed a high stability comparable to that containing (AD)A/T base pair. Destabilization
Pavel Kielkowski et al.
The Journal of organic chemistry, 76(9), 3457-3462 (2011-03-24)
(Cytosin-5-yl)ethynyl derivatives of pyrimidine and 7-deazaadenine 2-deoxyribonucleosides and nucleoside triphosphates (dNTPs) were prepared in one step by the aqueous Sonogashira coupling of unprotected halogenated nucleos(t)ides with 5-ethynylcytosine. The modified dNTPs were good substrates for DNA polymerases suitable for primer extension

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