699810
Poly(ethylene glycol) diacetylene
average MN 2,000, cross-linking reagent click chemistry, acetylene
Synonym(s):
Polyethylene glycol, PEG bis(4-pentynoate)terminated, PEG diacetylene, Poly(ethylene glycol) bis(4-pentynoate) terminated
About This Item
product name
Poly(ethylene glycol) diacetylene, average Mn 2,000
form
powder
mol wt
average Mn 2,000
reaction suitability
reagent type: cross-linking reagent
reaction type: click chemistry
mp
46-52 °C
Mw/Mn
~1.0
Ω-end
alkyne
α-end
alkyne
polymer architecture
shape: linear
functionality: homobifunctional
storage temp.
2-8°C
WGK
WGK 3
Flash Point(F)
>446.0 °F
Flash Point(C)
> 230 °C
Personal Protective Equipment
Regulatory Information
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Articles
Scaffold patterning with poly(ethylene glycol)-based hydrogels for cell presence in 2D and 3D environments on photoactive substrates.
Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
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