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471909

Sigma-Aldrich

(S)-(+)-Ketoprofen

99%

Synonym(s):

(S)-(+)-3-Benzoyl-α-methylbenzeneacetic acid, (S)-2-(3-Benzoylphenyl)propionic acid

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About This Item

Linear Formula:
C6H5COC6H4CH(CH3)CO2H
CAS Number:
22161-81-5
Molecular Weight:
254.28
MDL number:
MFCD00673316
UNSPSC Code:
12352115
PubChem Substance ID:
24870770
NACRES:
NA.22

Quality Level

100

Assay

99%

optical activity

[α]22/D +49°, c = 1 in methanol

mp

75-78 °C (lit.)

SMILES string

C[C@H](C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)/t11-/m0/s1

InChI key

DKYWVDODHFEZIM-NSHDSACASA-N

Gene Information

human ... IL8RA(3577) , PTGS1(5742) , PTGS2(5743)
mouse ... Ptgs2(19225)

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Related Categories

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H301,H315,H319,H335,H400

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Neonatal inflammation is common and has lasting consequences for adult health. We investigated the lasting effects of a single bout of neonatal inflammation on adult respiratory control in the form of respiratory motor plasticity induced by acute intermittent hypoxia, which
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The CXC chemokine CXCL8/IL-8 plays a major role in the activation and recruitment of polymorphonuclear (PMN) cells at inflammatory sites. CXCL8 activates PMNs by binding the seven-transmembrane (7-TM) G-protein-coupled receptors CXC chemokine receptor 1 (CXCR1) and CXC chemokine receptor 2
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Journal of separation science, 38(14), 2423-2430 (2015-05-02)
Valuable quantitative information could be obtained from strongly overlapped chromatographic profiles of two enantiomers by using proper chemometric methods. Complete separation profiles where the peaks are fully resolved are difficult to achieve in chiral separation methods, and this becomes a
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