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Key Documents

357898

Sigma-Aldrich

Serinol

98%

Synonym(s):

2-Amino-1,3-propanediol

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About This Item

Linear Formula:
HOCH2CH(NH2)CH2OH
CAS Number:
Molecular Weight:
91.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

CN¥376.36


Estimated to ship onMay 23, 2025Details


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Quality Level

Assay

98%

bp

277 °C (lit.)

mp

52-55 °C (lit.)

functional group

amine
hydroxyl

SMILES string

NC(CO)CO

InChI

1S/C3H9NO2/c4-3(1-5)2-6/h3,5-6H,1-2,4H2

InChI key

KJJPLEZQSCZCKE-UHFFFAOYSA-N

General description

Serinol activates toxin production in the attenuated cultures of Helminthosporium sacchari.[1] Preparation of polyesters derived from serinol is reported.[2]

Application

Serinol may be used to prepare the artificial nucleic acids.[3] It may be used in the synthesis of N-acylated serinol and C16-serinol affinity gel.[4]

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Hiroyuki Asanuma et al.
Chemical record (New York, N.Y.), 14(6), 1055-1069 (2014-08-30)
In this account, we demonstrate a new methodology for the de novo design of functional oligonucleotides with the acyclic scaffolds threoninol and serinol. Four functional motifs-wedge, interstrand-wedge, dimer, and cluster-have been prepared from natural DNA or RNA and functional base
F Pinkerton et al.
Proceedings of the National Academy of Sciences of the United States of America, 73(11), 4007-4011 (1976-11-01)
Successive transfer in synthetic medium of spores and mycelial fragments from original toxin-producing cultures of Helminthosporium sacchari results in attenuated cultures which do not produce the host-specific toxin helminthosporoside. When attenuated cultures are grown on material obtained from the water
Daniele Locatelli et al.
Nanomaterials (Basel, Switzerland), 10(6) (2020-06-21)
The solubility parameters of multiwalled carbon nanotubes (CNTs) was tuned via their chemical modification with pyrrole compounds (PyCs), by means of a simple and sustainable methodology. PyCs were synthesized with high atom efficiency through the Paal-Knorr reaction of primary amines
Yuichi Nakamura et al.
Organic letters, 15(2), 322-325 (2012-12-28)
Siladenoserinols A-L were isolated from a tunicate as inhibitors of p53-Hdm2 interaction, a promising target for cancer chemotherapy. Their structures including the absolute configurations were elucidated to be new sulfonated serinol derivatives, each of which contains a 6,8-dioxabicyclo[3.2.1]octane unit and
Xiaojin Zhang et al.
Macromolecular rapid communications, 33(8), 693-697 (2012-02-23)
A water-soluble polycarbonate with dimethylamino pendant groups, poly(2-dimethylaminotrimethylene carbonate) (PDMATC), is synthesized and characterized. First, the six-membered carbonate monomer, 2-dimethylaminotrimethylene carbonate (DMATC), is prepared via the cyclization reaction of 2-(dimethylamino)propane-1,3-diol with triphosgene in the presence of triethylamine. Although the attempted

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