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D18609

Sigma-Aldrich

1,3-Diamino-2-propanol

95%

Synonym(s):

2-Hydroxy-1,3-propanediamine, 1,3-Diamino-2-hydroxypropane

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About This Item

Linear Formula:
NH2CH2CH(OH)CH2NH2
CAS Number:
616-29-5
Molecular Weight:
90.12
Beilstein:
741859
EC Number:
210-474-2
MDL number:
MFCD00008142
UNSPSC Code:
12352100
PubChem Substance ID:
24893556
NACRES:
NA.22

Quality Level

200

Assay

95%

form

solid

mp

40-44 °C (lit.)

SMILES string

NCC(O)CN

InChI

1S/C3H10N2O/c4-1-3(6)2-5/h3,6H,1-2,4-5H2

InChI key

UYBWIEGTWASWSR-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

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Application

  • 1,3-Diamino-2-propanol is a versatile bidentate diamine ligand which is used in the synthesis of a variety of organometallic compounds.
  • It is a precursor to synthesize the fluorogenic dsDNA binder, N1,N3-bis(4-amidinophenyl)propane-1,3-diamine (BAPPA).
  • It can also be used as a branching unit in the synthesis of peptide dendrimers.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Synthesis and esterolytic activity of catalytic peptide dendrimers.
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The effect of diaminopropanol, an inhibitor of polyamine synthesis, on the metabolic response of liver to insulin was studied in streptozotocin-diabetic rats. Insulin elicited a prompt and very marked increase in ornithine and S-adenosylmethionine decarboxylase activities and in putrescine concentration.
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