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Merck
CN

275352

Sigma-Aldrich

2-Hydroxy-5-nitrobenzaldehyde

98%

Synonym(s):

5-Nitrosalicylaldehyde

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12 UNITS
CN¥1,072.68

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12 UNITS
CN¥1,072.68

About This Item

Linear Formula:
HOC6H3(NO2)CHO
CAS Number:
Molecular Weight:
167.12
Beilstein:
512565
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

CN¥1,072.68


Estimated to ship onJune 03, 2025Details


Request a Bulk Order

Quality Level

Assay

98%

mp

125-128 °C (lit.)

functional group

aldehyde
nitro

SMILES string

[H]C(=O)c1cc(ccc1O)[N+]([O-])=O

InChI

1S/C7H5NO4/c9-4-5-3-6(8(11)12)1-2-7(5)10/h1-4,10H

InChI key

IHFRMUGEILMHNU-UHFFFAOYSA-N

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1 of 4

This Item
13191013192095299
assay

34.5-36.5%

assay

-

assay

-

assay

≥35% (RT)

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

100

solubility

diethyl ether: soluble, water: soluble, petroleum ether: insoluble

solubility

-

solubility

-

solubility

-

reaction suitability

reagent type: oxidant

reaction suitability

reagent type: oxidant

reaction suitability

reagent type: oxidant

reaction suitability

reagent type: oxidant

density

1.130 g/cm3

density

1.13 g/cm3

density

1.13 g/cm3

density

1.13 g/mL at 20 °C

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

2-8°C

General description

2-Hydroxy-5-nitrobenzaldehyde is a nitroaromatic compound used to prepare Schiff base ligands.[1]

The interaction of 2-hydroxy-5-nitrobenzaldehyde and chlorogenic acid (CHL) with the components of the rat hepatic glucose 6-phosphatase system was studied[2].

Physical properties

Free of 3-nitro isomer

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Qing-Bin Li et al.
Acta chimica Slovenica, 64(2), 500-505 (2017-06-18)
Two mononuclear Schiff base manganese(III) complexes, [MnL(N3)(OH2)]·CH3OH (1) and [MnL(NCS)(OH2)] · H2O (2), where L is the dianionic form of N,N'-bis(5-nitrosalicylidene)ethane-1,2-diamine, have been prepared and characterized by elemental analysis, IR and UV-Vis spectroscopy and single crystal X-ray diffraction. The Mn
Synthesis, spectroscopic characterization and antimicrobial activity of mono-, bi-and tri-nuclear metal complexes of a new Schiff base ligand
Shebl M,et al.
Journal of Molecular Structure, 980, 39-50 (2010)
M A Pajares et al.
The Journal of biological chemistry, 264(12), 6804-6809 (1989-04-25)
The 11-cis-retinal binding site of rhodopsin is of great interest because it is buried in the membrane but yet must provide an environment for charged amino acids. In addition, the active-site lysine residue must be able to engage in rapid
W J Arion et al.
Archives of biochemistry and biophysics, 339(2), 315-322 (1997-03-15)
We have studied the interactions of chlorogenic acid (CHL) and 2-hydroxy-5-nitrobenzaldehyde (HNB) with the components of the rat hepatic glucose 6-phosphatase (Glc-6-Pase) system. CHL and HNB are competitive inhibitors of glucose 6-phosphate (Glc-6-P) hydrolysis in intact microsomes with Ki values
C J Van Noorden et al.
The Histochemical journal, 19(9), 483-487 (1987-09-01)
The histochemical fluorescence method using 5-nitrosalicylaldehyde for the demonstration of cathepsin B activity has been used. Precipitation of the fluorescent final reaction product was analysed continuously during incubation for cathepsin B activity. Unfixed cultured human fibroblasts as well as cryostat

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