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Merck
CN

258385

Protoporphyrin IX disodium salt

≥90% (HPLC)

Synonym(s):

3,7,12,17-Tetramethyl-8,13-divinyl-2,18-porphinedipropionic acid disodium salt, Depocolin-S, Ooporphyrin disodium salt

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About This Item

Empirical Formula (Hill Notation):
C34H32N4Na2O4
CAS Number:
Molecular Weight:
606.62
UNSPSC Code:
12352103
NACRES:
NA.23
PubChem Substance ID:
EC Number:
256-815-9
Beilstein/REAXYS Number:
5227034
MDL number:
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Quality Level

assay

≥90% (HPLC)

form

powder

λmax

406 nm

storage temp.

2-8°C

SMILES string

[Na+].[Na+].Cc1c(CCC([O-])=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(C=C)c5C)c(C=C)c4C)c(C)c3CCC([O-])=O

InChI

1S/C34H34N4O4.2Na/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16,36-37H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);;/q;2*+1/p-2/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;

InChI key

JZRNDUPVNXWZDY-HXFTUNQESA-L

Application

Protoporphyrin disodium salt (PpIX) was used as a dye content for fluorescence spectroscopic characterization in a study. The cytotoxic effect of PpIX on sarcoma 180 solid tumors cells was reported in a study.

Features and Benefits

  • High purity (≥90% HPLC)
  • Operates effectively within a wavelength range of 403-409 nm
  • Exhibits a high extinction coefficient of ≥120,000
  • Available in multiple pack sizes


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Novel Graphene‑Based Nanostructures Production, Functionalization, and Engineering


Fluorescence spectroscopic characterization of salivary metabolites of oral cancer patients.
Yuvaraj M, et al.
Journal of Photochemistry and Photobiology. B, Biology, 130, 153-160 (2014)
Sonodynamic effects of protoporphyrin IX disodium salt on isolated sarcoma 180 cells
Liu Q, et al.
Ultrasonics, 45(1-4), 56-60 (2006)
Hirotsugu Kobuchi et al.
PloS one, 7(11), e50082-e50082 (2012-11-29)
Accumulation of protoporphyrin IX (PpIX) in malignant cells is the basis of 5-aminolevulinic acid (ALA)-mediated photodynamic therapy. We studied the expression of proteins that possibly affect ALA-mediated PpIX accumulation, namely oligopeptide transporter-1 and -2, ferrochelatase and ATP-binding cassette transporter G2



Global Trade Item Number

SKUGTIN
258385-1G04061826061732
258385-5G04061833605790
258385-250MG04061826061763