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Merck
CN

159158

Acetamidine hydrochloride

95%

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About This Item

Linear Formula:
CH3C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
94.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-700-9
Beilstein/REAXYS Number:
3591762
MDL number:
Assay:
95%
Form:
solid
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InChI key

WCQOBLXWLRDEQA-UHFFFAOYSA-N

InChI

1S/C2H6N2.ClH/c1-2(3)4;/h1H3,(H3,3,4);1H

SMILES string

Cl[H].CC(N)=N

assay

95%

form

solid

mp

165-170 °C (lit.)

functional group

amidine

Quality Level

General description

Acetamidine hydrochloride is an amidine salt and its conversion to 2,4,6-trimethyl-sym-triazine has been studied.

Application

Acetamidine hydrochloride was used in the preparation of decarboxyectoine. It was also used in the synthesis of ethyl 4-(4-hydroxyphenyl)methylidene-2-methyl-5-oxo-1-imidazolacetate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Synthesis of the sym-Triazine System. I. Trimerization and Cotrimerization of Amidines.
Schaefer FC, et al.
Journal of the American Chemical Society, 81(6), 1466-1470 (1959)
H Niwa et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(24), 13617-13622 (1996-11-26)
The jellyfish Aequorea victoria possesses in the margin of its umbrella a green fluorescent protein (GFP, 27 kDa) that serves as the ultimate light emitter in the bioluminescence reaction of the animal. The protein is made up of 238 amino
Michael Schnoor et al.
Biochemical and biophysical research communications, 322(3), 867-872 (2004-09-01)
Different substances such as dimethyl sulfoxide, tetramethylene sulfoxide, 2-pyrollidone, and the naturally occurring compatible solute betaine enhance PCR amplification of GC-rich DNA templates with high melting temperatures. In particular, cyclic compatible solutes outperform traditional PCR enhancers. We therefore investigated the
Four-component synthesis of fully substituted 1,2,4-triazoles.
Steven T Staben et al.
Angewandte Chemie (International ed. in English), 49(2), 325-328 (2009-12-10)
A Danan et al.
Farmaco (Societa chimica italiana : 1989), 52(4), 227-229 (1997-04-01)
A set of heterocyclic N-acetamidinium hydrochlorides were prepared from the corresponding N-acetonitriles. The antiparasitic screening showed that, while all amidines are practically inactive, some nitriles present leishmanicide properties.

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