- Synthesis and antiparasitic activities of amidinic azolated derivatives.
Synthesis and antiparasitic activities of amidinic azolated derivatives.
Farmaco (Societa chimica italiana : 1989) (1997-04-01)
A Danan, D Charon, S Kirkiacharian, C Bories, P M Loiseau
PMID9241827
ABSTRACT
A set of heterocyclic N-acetamidinium hydrochlorides were prepared from the corresponding N-acetonitriles. The antiparasitic screening showed that, while all amidines are practically inactive, some nitriles present leishmanicide properties.
MATERIALS