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About This Item
Linear Formula:
FC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
185.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥90%
mp
140-145 °C (lit.)
functional group
carboxylic acid
fluoro
nitro
SMILES string
OC(=O)c1ccc(F)cc1[N+]([O-])=O
InChI
1S/C7H4FNO4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,(H,10,11)
InChI key
YLUCXHMYRQUERW-UHFFFAOYSA-N
Application
4-Fluoro-2-nitrobenzoic acid has been used to study the reactions of substituted pyridines with the salicyl phosphate dianion.
Biochem/physiol Actions
4-Fluoro-2-nitrobenzoic acid enhances the binding of insulin to adipocytes.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Intramolecular general acid catalysis of phosphate monoester hydrolysis. The hydrolysis of salicyl phosphate.
J. Chem. Soc. Perkin Trans. II, 2, 149-155 (1972)
P E Phillips et al.
The Journal of biological chemistry, 263(23), 11175-11182 (1988-08-15)
Insulin binding to isolated rat white adipocytes at 15 degrees C, a temperature at which cellular degradation of insulin is negligible, has been found to be described by the Two-step Binding Model: R + I in equilibrium RI in equilibrium
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