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Merck
CN

UTRN

utrophin

别名:
DMDL, DRP, DRP1
物种:
UniProtKB ID:
基因ID:
  • Human(7402) Summary: This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
  • Mouse(22288) utrophin
  • Rat(25600) utrophin
  • chicken(421610) utrophin
  • Zebrafish(100034367) utrophin
  • sheep(101120168) utrophin
  • cow(534358) utrophin
  • domestic cat(101096570) utrophin
  • dog(442965) utrophin
  • naked mole-rat(101717283) utrophin
  • domestic guinea pig(100731640) utrophin

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Antibodies

货号
说明
物种反应性
应用
Anti-Utrophin A, from rabbit,
物种反应性
human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
Anti-Utrophin Antibody, clone MANCHO3 (8A4), ,
物种反应性
canine, human, mouse
应用
immunofluorescence
immunohistochemistry

western blot
Anti-UTRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Utrn,
物种
mouse
MISSION® esiRNA, targeting human UTRN,
物种
human