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Merck
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PTGER4

prostaglandin E receptor 4 (subtype EP4)

别名:
EP4, EP4R
物种:
UniProtKB ID:
基因ID:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)

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Small Molecule - Agonist

货号
说明
物种
前列腺素E2, European Pharmacopoeia (EP) Reference Standard,
物种
human
前列腺素 E1, ≥98% (HPLC), synthetic,
物种
human, mouse
前列腺素 E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
物种
human, mouse
前列腺素 E1, synthetic, powder, BioReagent, suitable for cell culture,
物种
human, mouse
前列腺素E2, synthetic, powder, BioReagent, suitable for cell culture,
物种
human, mouse

Small Molecule - Antagonist

货号
说明
物种
前列腺素 E1, ≥98% (HPLC), synthetic,
物种
human, mouse
前列腺素 E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
物种
human, mouse
前列腺素 E1, synthetic, powder, BioReagent, suitable for cell culture,
物种
human, mouse
前列腺素E2, synthetic, powder, BioReagent, suitable for cell culture,
物种
human, mouse
前列腺素E2, γ-irradiated, powder, BioXtra, suitable for cell culture,
物种
human, mouse

Antibodies

货号
说明
物种反应性
应用
Anti-PTGER4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
canine, human
应用
ELISA
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence

western blot

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
前列腺素E2, ≥93% (HPLC), synthetic,
物种
mouse, human
吲哚美辛, 98.5-100.5% (in accordance with EP),
物种
human, mouse, rat

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PTGER4,
物种
human
MISSION® esiRNA, targeting mouse Ptger4,
物种
mouse