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Merck
CN

PRKCB

protein kinase C, beta

别名:
PKC-beta, PKCB, PRKCB1, PRKCB2
物种:
UniProtKB ID:
基因ID:
  • Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(18751) protein kinase C, beta
  • Rat(25023) protein kinase C, beta
  • Domestic Rabbit(100037719) protein kinase C, beta
  • sheep(101118410) protein kinase C, beta
  • naked mole-rat(101722702) protein kinase C, beta
  • domestic cat(101088970) protein kinase C, beta
  • chicken(416567) protein kinase C, beta
  • dog(489968) protein kinase C, beta
  • cow(282325) protein kinase C, beta

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Small Molecule - Agonist

货号
说明
物种
油酸, ≥99% (GC),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-PKCβ Antibody, clone 2E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-p-PKCβ (Ser660) Antibody, clone 2C11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, human, monkey, mouse, rabbit, rat
应用
affinity binding assay
immunocytochemistry

inhibition assay

western blot
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-PRKCB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
ANTI-PKC BETA1/2 (CENTER) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
immunohistochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
Hispidin, solid, ≥98% (HPLC),
物种
human
H-7 dihydrochloride, ≥98% (HPLC),
物种
human
油酸, ≥99% (GC),
物种
human
GSK690693, ≥98% (HPLC),
物种
human

Proteins

货号
说明
物种
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRKCB,
物种
human
MISSION® esiRNA, targeting mouse Prkcb,
物种
mouse