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EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

别名:
4E-BP1, 4EBP1, BP-1, PHAS-I
物种:
Human EIF4EBP1 (1978), Mouse Eif4ebp1 (13685), Rat Eif4ebp1 (116636), domestic cat EIF4EBP1 (101088571), Goat EIF4EBP1 (100861097), dog EIF4EBP1 (475590), chicken EIF4EBP1 (426773), domestic guinea pig Eif4ebp1 (100733182), Zebrafish eif4ebp1 (799566), sheep EIF4EBP1 (101111426) ...展开
UniProtKB ID:
Q13541, B2R502, D3DSW8, Q6IBN3
基因ID:
  • Human(1978) Summary: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]
  • Mouse(13685) eukaryotic translation initiation factor 4E binding protein 1
  • Rat(116636) eukaryotic translation initiation factor 4E binding protein 1
  • domestic cat(101088571) eukaryotic translation initiation factor 4E binding protein 1
  • Goat(100861097) eukaryotic translation initiation factor 4E binding protein 1
  • dog(475590) eukaryotic translation initiation factor 4E binding protein 1
  • chicken(426773) eukaryotic translation initiation factor 4E binding protein 1
  • domestic guinea pig(100733182) eukaryotic translation initiation factor 4E binding protein 1
  • Zebrafish(799566) eukaryotic translation initiation factor 4E binding protein 1
  • sheep(101111426) eukaryotic translation initiation factor 4E binding protein 1
  • cow(509613) eukaryotic translation initiation factor 4E binding protein 1
  • naked mole-rat(101710614) eukaryotic translation initiation factor 4E binding protein 1

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Antibodies

货号
说明
物种反应性
应用
ABE2889M
Anti-phospho 4E-BP1 (Ser83), ,
物种反应性
human
应用
flow cytometry
immunocytochemistry
immunofluorescence
western blot
SAB4301339
Anti-phospho-4E-BP1 (pThr70) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
SAB4500736
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
SAB4500739
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
SAB4500740
Anti-4E-BP1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot

Proteins

货号
说明
物种
SRP0253
4EBP1 Active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
物种
human
SRP5161
4EBP1, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
SRP5162
4EBP1，His 标记 人, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU029571
MISSION® esiRNA, targeting mouse Eif4ebp1,
物种
mouse
EHU150481
MISSION® esiRNA, targeting human EIF4EBP1,
物种
human