CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
别名:
ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1
物种:
Human CFTR (1080), Mouse Cftr (12638), Rat Cftr (24255), domestic cat CFTR (492308), dog CFTR (492302), chicken CFTR (100049619), Zebrafish cftr (559080), Domestic Rabbit CFTR (100009471), sheep CFTR (443347), cow CFTR (281067) ...展开
UniProtKB ID:
基因ID:
- Human(1080) Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008]
- Mouse(12638) cystic fibrosis transmembrane conductance regulator
- Rat(24255) cystic fibrosis transmembrane conductance regulator
- domestic cat(492308) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- dog(492302) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- chicken(100049619) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- Zebrafish(559080) cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
- Domestic Rabbit(100009471) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- sheep(443347) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- cow(281067) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- Horse(100071259) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- naked mole-rat(101709472) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
- domestic guinea pig(100135647) cystic fibrosis transmembrane conductance regulator homolog
- domestic guinea pig(100719898) cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
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Antibodies
货号
说明
物种反应性
应用
Anti-CFTR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
抗CFTR抗体，a.a.1370-1380，克隆M3A7, clone M3A7, Chemicon®, from mouse,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗-CFTR抗体，克隆M3A7, clone M3A7, Upstate®, from mouse,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CFTR Antibody, clone MM13-4, clone MM13-4, Upstate®, from mouse,
物种反应性
human
应用
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-CFTR Antibody, clone MM13-4 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, porcine
应用
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot