跳转至内容
Merck
CN

CDK9

cyclin-dependent kinase 9

别名:
C-2k, CDC2L4, CTK1, PITALRE, TAK
物种:
UniProtKB ID:
基因ID:
  • Human(1025) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]
  • Mouse(107951) cyclin-dependent kinase 9 (CDC2-related kinase)
  • Rat(362110) cyclin-dependent kinase 9
  • domestic guinea pig(100725846) cyclin-dependent kinase 9
  • naked mole-rat(101722666) cyclin-dependent kinase 9
  • sheep(101109788) cyclin-dependent kinase 9
  • Zebrafish(321602) cyclin-dependent kinase 9 (CDC2-related kinase)
  • cow(520580) cyclin-dependent kinase 9
  • dog(491325) cyclin-dependent kinase 9
  • chicken(417226) cyclin-dependent kinase 9
  • fruit fly(37586) Cyclin-dependent kinase 9
  • domestic cat(101097767) cyclin-dependent kinase 9

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-CDK9 Antibody, clone 1F9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, mouse, rat
应用
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
抗-CDK9 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-phospho-CDK9 (pThr186) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-CDK9 antibody produced in rabbit, ,
物种反应性
应用
immunohistochemistry
western blot
Rabbit anti-CDK9 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物种反应性
human, mouse
应用
immunohistochemistry
immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

货号
说明
物种
核抑制剂, ≥98% (TLC),
物种
human, mouse, rat
奥罗莫星, ≥98% (HPLC),
物种
human, rat

Proteins

货号
说明
物种
Cdk9/Cyclin T1 Protein, active, 10 µg, Active, C-terminal 6His-tagged, full length recombinant, human Cdk9 co-expressed with untagged, full-length human Cyclin T1, for use in Kinase Assays.,
物种
human
CDK9/CyclinK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CDK9,
物种
human