R7772
核抑制剂
synthetic (organic), ≥98% (TLC), cyclin-dependent kinases inhibitor, powder
别名:
2-（R）- [[9-（1-甲基乙基）-6 - [（苯基甲基）氨基] -9H-嘌呤-2-基〕氨基〕-1-丁醇, 6-（苄基氨基）-2（R）- [[1-（羟甲基）丙基]氨基]-9-异丙基
选择规格
关于此项目
产品名称
核抑制剂, ≥98% (TLC)
biological source
synthetic (organic)
assay
≥98% (TLC)
form
powder
mp
106-107 °C
solubility
chloroform: 50 mg/mL, clear, colorless to light yellow
storage temp.
−20°C
SMILES string
CC[C@H](CO)Nc1nc(NCc2ccccc2)c3ncn(C(C)C)c3n1
InChI
1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1
InChI key
BTIHMVBBUGXLCJ-OAHLLOKOSA-N
Gene Information
human ... CDK1(983), CDK2(1017), CDK5(1020), CDK7(1022), CDK9(1025), CDKN1A(1026), CDKN1B(1027), CDKN1C(1028), CDKN2A(1029), CDKN2B(1030), CDKN2C(1031), CDKN2D(1032), CDKN3(1033)
mouse ... CDK1(12534)
rat ... CDK1(54237)
Application
- 作为p34cdc2/cyclin B激酶抑制剂对猪卵母细胞进行预培养
- 作为TCM199培养基的补充剂，用于成年山羊的卵-卵母细胞复合体（COC）的体外早熟化
- 作为细胞周期蛋白依赖性激酶5（CDK5）抑制剂用于星形胶质细胞条件培养基中
- 作为CDK2抑制剂加入培养基中以处理hESC细胞
Biochem/physiol Actions
Features and Benefits
Legal Information
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)