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Merck
CN

CDK7

cyclin-dependent kinase 7

别名:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
物种:
UniProtKB ID:
基因ID:
  • Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
  • Mouse(12572) cyclin-dependent kinase 7
  • Rat(171150) cyclin-dependent kinase 7
  • domestic guinea pig(100725955) cyclin-dependent kinase 7
  • naked mole-rat(101702664) cyclin-dependent kinase 7
  • sheep(101119934) cyclin-dependent kinase 7
  • Horse(100049964) cyclin-dependent kinase 7
  • Zebrafish(405897) cyclin-dependent kinase 7
  • dog(608441) cyclin-dependent kinase 7
  • domestic cat(101086781) cyclin-dependent kinase 7
  • chicken(771294) cyclin-dependent kinase 7
  • cow(515462) cyclin-dependent kinase 7
  • fruit fly(31441) Cyclin-dependent kinase 7

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Antibodies

货号
说明
物种反应性
应用
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
物种反应性
human
应用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

microarray

western blot
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
抗磷酸化细胞周期蛋白依赖性激酶7(Thr170)抗体, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
ChIP
western blot
Anti-CDK7 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CDK7 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA

Small Molecule - Inhibitor

货号
说明
物种
核抑制剂, ≥98% (TLC),
物种
human, mouse, rat
奥罗莫星, ≥98% (HPLC),
物种
human, rat

Proteins

货号
说明
物种
Cdk7/Cyclin H/MAT1 (CAK complex) Protein, active, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
物种
human
CDK7/Cyclin H1/MNAT1, active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Cdk7,
物种
mouse
MISSION® esiRNA, targeting human CDK7,
物种
human

Small Molecule - Substrate

货号
说明
物种
Cdk7/9tide, ,
物种
human