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Merck
CN

CACNA2D4

calcium channel, voltage-dependent, alpha 2/delta subunit 4

别名:
RCD4
物种:
UniProtKB ID:
基因ID:
  • Human(93589) Summary: This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
  • Mouse(319734) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • Rat(312668) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • chicken(100858946) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • domestic guinea pig(100716046) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • Horse(100630648) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • domestic cat(101095834) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • dog(477733) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • sheep(101116306) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • naked mole-rat(101705589) calcium channel, voltage-dependent, alpha 2/delta subunit 4
  • cow(784075) calcium channel, voltage-dependent, alpha 2/delta subunit 4

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Small Molecule - Allosteric Modulator

货号
说明
物种
加巴喷丁, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
加巴喷丁标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
加巴喷丁, United States Pharmacopeia (USP) Reference Standard,
物种
human
普瑞巴林, European Pharmacopoeia (EP) Reference Standard,
物种
human
加巴喷丁, European Pharmacopoeia (EP) Reference Standard,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-CACNA2D4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
苄普地尔 盐酸盐, powder,
物种
human
Terodiline hydrochloride, ≥98% (HPLC), solid,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CACNA2D4,
物种
human