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Merck
CN
所有图片(1)

文件

B5016

Sigma-Aldrich

苄普地尔 盐酸盐

powder

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别名:
1-异丁氧基-2-吡咯烷基-3-（N-苄基苯胺）丙烷 盐酸盐
经验公式（希尔记法）:
C24H34N2O · HCl
CAS号:
68099-86-5
分子量:
403.00
MDL编号:
MFCD00065498
UNSPSC代码:
12352200
PubChem化学物质编号:
24277824
NACRES:
NA.77

形式

powder

质量水平

100

创始人

Johnson & Johnson

SMILES字符串

Cl.CC(C)COCC(CN(Cc1ccccc1)c2ccccc2)N3CCCC3

InChI

1S/C24H34N2O.ClH/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22;/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3;1H

InChI key

JXBBWYGMTNAYNM-UHFFFAOYSA-N

基因信息

human ... CACNA1A(773) , CACNA1B(774) , CACNA1C(775) , CACNA1D(776) , CACNA1E(777) , CACNA1F(778) , CACNA1G(8913) , CACNA1H(8912) , CACNA1I(8911) , CACNA1S(779) , CACNA2D1(781) , CACNA2D2(9254) , CACNA2D3(55799) , CACNA2D4(93589) , CACNB1(782) , CACNB2(783) , CACNB3(784) , CACNB4(785) , CACNG1(786) , CACNG2(10369) , CACNG3(10368) , CACNG4(27092) , CACNG5(27091) , CACNG6(59285) , CACNG7(59284) , CACNG8(59283)

生化/生理作用

非选择性钙通道阻滞剂和 IV 类抗心律失常药；抑制Na+-Ca2+ 交换；体外抑制脑肿瘤细胞的生长。

特点和优势

该化合物由 Johnson & Johnson 开发。如需浏览其他制药公司开发的化合物和批准的药物/候选药物列表，请点击此处。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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The two proteases beta-secretase and gamma-secretase generate the amyloid beta peptide and are drug targets for Alzheimer's disease. Here we tested the possibility of targeting the cellular environment of beta-secretase cleavage instead of the beta-secretase enzyme itself. beta-Secretase has an
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