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Merck
CN

ANPEP

alanyl (membrane) aminopeptidase

别名:
APN, CD13, GP150, LAP1, P150, PEPN
物种:
UniProtKB ID:
基因ID:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase

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ELISA

货号
说明
物种
Human Aminopeptidase N ELISA, for serum, plasma and cell culture supernatants,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-ANPEP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

western blot
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
物种反应性
human
应用
flow cytometry
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
物种反应性
human, nonhuman primates
应用
flow cytometry
immunohistochemistry

immunoprecipitation (IP)
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
物种反应性
human, pig, rabbit
应用
flow cytometry
immunohistochemistry
Anti-APN/CD13 Antibody, clone 1D20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, rat
应用
affinity binding assay
flow cytometry

immunohistochemistry

western blot

Small Molecule - Inhibitor

货号
说明
物种
放线酰胺素, ,
物种
human
黄酮, ≥99.0%,
物种
human, rat, mouse

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Anpep,
物种
mouse
MISSION® esiRNA, targeting human ANPEP,
物种
human