product name
放线酰胺素,
生物来源
synthetic (organic)
质量水平
检测方案
≥98% (TLC)
形式
powder
溶解性
ethanol: 50 mg/mL, clear, colorless
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
enzyme | inhibits
储存温度
−20°C
SMILES字符串
CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO
InChI
1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)
InChI key
XJLATMLVMSFZBN-UHFFFAOYSA-N
基因信息
human ... ANPEP(290) , DPP4(1803) , ECE1(1889) , LAP3(51056)
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WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor
Biochemistry, 39(6), 1256-1262 (2000)
Ligand-induced changes in the structure and dynamics of Escherichia coli peptide deformylase
Biochemistry, 48(32), 7595-7607 (2009)
Scientific reports, 10(1), 6358-6358 (2020-04-15)
Vaginal delivery with obstetrical trauma is a risk factor for pelvic organ prolapse later in life. Loss of fibulin-5 (FBLN5), an elastogenesis-promoting cellular matrix protein, results in prolapse in mice. Here, we evaluated effects of pregnancy, parturition, and obstetrical injury
Microbes and infection, 12(5), 415-419 (2010-02-17)
The biosynthesis of proteins with N-terminal formylated methionine residues and subsequent protein deformylation are unique and invariant bacterial processes. They are exploited by the capacity of the human innate immune system to sense formylated peptides (FPs) and targeted by the
PLoS biology, 9(5), e1001066-e1001066 (2011-06-02)
For several decades, molecular recognition has been considered one of the most fundamental processes in biochemistry. For enzymes, substrate binding is often coupled to conformational changes that alter the local environment of the active site to align the reactive groups
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