推荐产品
产品名称
L -缬氨酸, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
生物来源
non-animal source
质量水平
Agency
USP/NF
meets EP testing specifications
meets JP testing specifications
meets USP testing specifications
方案
98.5-101.0%
表单
powder
质量
meets EP, JP, USP testing specifications
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
颜色
white
mp
295-300 °C (subl.) (lit.)
溶解性
H2O: 25 mg/mL
应用
pharmaceutical (small molecule)
SMILES字符串
CC(C)[C@H](N)C(O)=O
InChI
1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m0/s1
InChI key
KZSNJWFQEVHDMF-BYPYZUCNSA-N
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相关类别
应用
L-缬氨酸已用于制备培养原代肝细胞的氨基酸补充培养基。
生化/生理作用
缬氨酸是必需氨基酸，参与谷氨酰胺和丙氨酸的生物合成。缬氨酸是一种支链氨基酸（BCAA），在 BCAA 之间保持平衡。L-缬氨酸用作能量燃料。L-缬氨酸的长期缺乏导致生长障碍、器官损伤和肌肉质量损失。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Martin Kohlmeier
Nutrient Metabolism: Structures, Functions, and Genes, 390-390 (2015)
Recapitulation of metabolic defects in a model of propionic acidemia using patient-derived primary hepatocytes.
Chapman KA
Molecular Genetics and Metabolism, 117(3), 355-362 (2016)
Shankar Sachidhanandam et al.
Nature neuroscience, 16(11), 1671-1677 (2013-10-08)
Neocortical activity can evoke sensory percepts, but the cellular mechanisms remain poorly understood. We trained mice to detect single brief whisker stimuli and report perceived stimuli by licking to obtain a reward. Pharmacological inactivation and optogenetic stimulation demonstrated a causal
Ihab Daou et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(47), 18631-18640 (2013-11-22)
We report a novel model in which remote activation of peripheral nociceptive pathways in transgenic mice is achieved optogenetically, without any external noxious stimulus or injury. Taking advantage of a binary genetic approach, we selectively targeted Nav1.8(+) sensory neurons for
Sonia Jego et al.
Nature neuroscience, 16(11), 1637-1643 (2013-09-24)
Rapid-eye movement (REM) sleep correlates with neuronal activity in the brainstem, basal forebrain and lateral hypothalamus. Lateral hypothalamus melanin-concentrating hormone (MCH)-expressing neurons are active during sleep, but their effects on REM sleep remain unclear. Using optogenetic tools in newly generated
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