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方案
≥95% (HPLC)
表单
powder
颜色
white to off-white
溶解性
DMSO: >20 mg/mL
储存温度
room temp
应用
Tomatine has been used as a standard for HPLC-based determination of tomatine from red and green tomatoes1. It has also been used to study its teratogenic effect using frog embryos2.
生化/生理作用
When the pure compounds were isolated, alpha-Tomatine was highly effective in inhibiting all of the cell lines, whereas dehydrotomatine, tomatidenol, and tomatidine had little, if any, effect on cell inhibition. It had been previously shown that commercial tomatine, which is customarily an approximate 10:1 mixture of α-tomatine and dehydrotomatine, strongly inhibits the growth of both colon and liver cancer cells.
制备说明
Tomatine hydrate is soluble in DMSO at a concentration that is greater than 20 mg/ml.
J M Medina et al.
Parasitology, 139(10), 1253-1265 (2012-06-22)
Leishmaniasis is a set of clinically distinct infectious diseases caused by Leishmania, a genus of flagellated protozoan parasites, that affects ~12 million people worldwide, with ~2 million new infections annually. Plants are known to produce substances to defend themselves against
Yukio Fujiwara et al.
Journal of agricultural and food chemistry, 60(10), 2472-2479 (2012-01-10)
It was previously revealed that esculeoside A, a new glycoalkaloid, and esculeogenin A, a new aglycon of esculeoside A, contained in ripe tomato ameliorate atherosclerosis in apoE-deficent mice. This study examined whether tomatidine, the aglycone of tomatine, which is a
Suk Hyun Choi et al.
Journal of agricultural and food chemistry, 60(15), 3891-3899 (2012-04-10)
Partial acid hydrolysis of the tetrasaccharide (lycotetraose) side chain of the tomato glycoalkaloid α-tomatine resulted in the formation of four products with three, two, one, and zero carbohydrate side chains, which were separated by high-performance liquid chromatography (HPLC) and identified
Kyeong-Mi Choi et al.
The Journal of nutritional biochemistry, 24(1), 335-342 (2012-09-15)
Obesity is a risk factor for numerous metabolic disorders. Recently, natural compounds that may be beneficial for improving obesity have received increasing attention. In this study, we investigated whether red and green tomato extracts attenuate high-fat-diet-induced obesity in C57BL/6 mice.
Hideyuki Manabe et al.
Chemical & pharmaceutical bulletin, 59(11), 1406-1408 (2011-11-02)
In the conventional method of mixer blending extraction, the yields of the tomato-saponin, esculeoside A, in the mini and middy tomatoes were found to be 0.043% and 0.046%, respectively. In order to improve the yields, we attempted a more efficient
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