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Merck
CN

SRP5164

Sigma-Aldrich

BAD, GST tagged human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

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别名:
BBC2, BCL2L8
UNSPSC代码:
12352202
NACRES:
NA.32

生物来源

human

重组

expressed in baculovirus infected Sf9 cells

检测方案

≥70% (SDS-PAGE)

形式

buffered aqueous glycerol solution

分子量

~47 kDa

NCBI登记号

应用

cell analysis

运输

dry ice

储存温度

−70°C

基因信息

human ... BAD(572)

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Autoimmune Type 1 Diabetes
Diabetes (2016)
Breast Cancer Cell Proliferation Is Inhibited by BAD
The Journal of Biological Chemistry (2007)
BAD overexpression inhibits cell growth and induces apoptosis via mitochondrial-dependent pathway in non-small cell lung cancer
Li Jiang
Cancer Cell International (2013)
Phosphorylation of p90 Ribosomal S6 Kinase (RSK) Regulates Extracellular Signal-Regulated Kinase Docking and RSK Activity
Philippe P
Molecular and Cellular Biochemistry (2003)
Romaine Fernando et al.
The Journal of biological chemistry, 282(39), 28864-28873 (2007-08-03)
Recent investigations suggest that functions of the proapoptotic BCL2 family members, including BAD, are not limited to regulation of apoptosis. Here we demonstrate that BAD inhibits G(1) to S phase transition in MCF7 breast cancer cells independent of apoptosis. BAD

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