产品名称
兔抗组蛋白H3 K27M单克隆抗体, recombinant, expressed in HEK 293 cells, clone RM192, purified immunoglobulin
recombinant
expressed in HEK 293 cells
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
RM192, monoclonal
recombinant monoclonal
form
buffered aqueous glycerol solution
species reactivity
human
technique(s)
ELISA: 0.5-2 μg/mL
immunocytochemistry: 0.005-0.1 μg/mL
immunohistochemistry: 0.005-0.1 μg/mL
western blot: 0.01-1 μg/mL
isotype
IgG
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
mutation (Lys27Met)
Gene Information
human ... H3C1(8350)
Biochem/physiol Actions
该抗体可与组蛋白H3 K27M突变体反应。与野生型组蛋白H3无交叉反应性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
Immunogen
对应于组蛋白H3 K27M突变体的肽。
Physical form
溶于含有50%甘油、1%BSA和0.09%叠氮化钠的磷酸盐缓冲盐水中。
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存储类别
10 - Combustible liquids
wgk
WGK 2
法规信息
常规特殊物品
含少量动物源组分生物产品
此项目有
Angela N Viaene et al.
Brain pathology (Zurich, Switzerland), 31(1), 45-60 (2020-07-19)
Congenital brain tumors are rare accounting for 0.5%-1.9% of all pediatric brain tumors. While different criteria have been used to classify a tumor as congenital, those diagnosed prior to 6 months of age are considered to be "probably" congenital in origin.
N Kfoury-Beaumont et al.
BMC biology, 20(1), 124-124 (2022-06-01)
Neurodevelopmental disorders increase brain tumor risk, suggesting that normal brain development may have protective properties. Mutations in epigenetic regulators are common in pediatric brain tumors, highlighting a potentially central role for disrupted epigenetic regulation of normal brain development in tumorigenesis.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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