¥1,859.99
推荐产品
生物来源
rabbit
质量水平
重组
expressed in proprietary host
偶联物
unconjugated
抗体形式
tissue culture supernatant
抗体产品类型
primary antibodies
克隆
SP2, monoclonal
种属反应性
human (tested)
种属反应性(根据同源性预测)
bovine, rabbit, pig
技术
immunohistochemistry: 1:400
1 of 4
此商品 | F3879 | F6755 | F8630 |
---|---|---|---|
biological source human plasma | biological source human plasma | biological source rat plasma | biological source bovine plasma |
form powder | form powder | form powder | form powder |
Gene Information human ... FGA(2243), FGB(2244), FGG(2266) | Gene Information human ... FGA(2243), FGB(2244), FGG(2266) | Gene Information rat ... Fga(361969), Fgb(24366), Fgg(24367) | Gene Information cow ... FGA(522039), FGB(510522), FGG(280792) |
UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 300 |
一般描述
Progesterone receptor (PGR) belongs to the steroid/thyroid hormone receptor family of ligand-activated transcription factors. It possesses the amino-terminal AF1 region, the central DNA-binding domain (DBD) and the carboxyl-terminal ligand- binding domain (LBD). The PGR gene is localized on human chromosome 11q22.1.
免疫原
生化/生理作用
which modulates the transcription of target genes in response to progesterone and other hormones. It is phosphorylated on multiple sites and at times, the phosphorylation changes according to the hormone involved. During hormone unavailability, PGR is bound to heat shock proteins. When the ligand binds, it causes the release of PGR from heat shock proteins. It is then translocated to the nucleus, where it binds to its DNA response elements (SREs) and to the components of the transcription machinery. PGR also binds to chromatin templates and results in chromatin remodeling adjacent to the PGR-binding sites.
特点和优势
外形
免责声明
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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