推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 48 kDa
种属反应性
mouse, rat, human
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pTyr185)
基因信息
human ... MAPK10(5602) , MAPK8(5599) , MAPK9(5601)
一般描述
MAPK9 (mitogen-activated protein kinase 9)/JNK2 (C-Jun N-terminal kinase 2)/ stress-activated protein kinase 2 (SAPK2) spans around 58494bp. The JNK2 gene is located on human chromosome 5q35. It has 17 introns.
免疫原
The antiserum was produced against synthesized peptide derived from human SAPK/JNK around the phosphorylation site of Tyr185.
Immunogen Range: 151-200
Immunogen Range: 151-200
生化/生理作用
Stress-activated protein kinase 2 (SAPK2) participates in proliferation, differentiation, apoptosis, migration, transcriptional regulation and development. It controls the cellular acidic/lysosomal cellular compartment. JNK2 plays an important role in mediating stress-induced apoptosis and modulating gene expression.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
JNK2 is activated during ER stress and promotes cell survival
Raciti M, et al.
Cell Death & Disease (2012)
MAPK9 (mitogen-activated protein kinase 9)
Chen F
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2003)
Junhui Liu et al.
Annals of translational medicine, 9(3), 260-260 (2021-03-13)
Kiaa0101, a regulator of cell proliferation, is overexpressed in many malignant tumors. However, its role in promoting invasion of glioma is poorly understood. Here, we investigated the effects of Kiaa0101 on glioma invasion and elucidated the underlying mechanisms of action.
Chin-Feng Hsuan et al.
Molecules (Basel, Switzerland), 25(24) (2020-12-17)
The proliferation and migration of vascular smooth muscle cells (VSMCs) are essential in the pathogenesis of various vascular diseases, such as atherosclerosis and restenosis. Among the mediators of VSMC during atherosclerosis development, platelet-derived growth factor (PDGF)-BB is a potent mitogen
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