生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 43 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunofluorescence: 1:100-1:500
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PTGER3(5733)
一般描述
The PTGER3 (prostaglandin E receptor 3) gene is mapped to human chromosome 1p31.1 and encodes a Gαi coupled receptor protein. It is predominantly localized to the brain in the neurons and activated glial cells. Anti-PTGER3 antibody detects endogenous levels of total PTGER3 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human PTGER3.
Immunogen Range: 16-65
Immunogen Range: 16-65
生化/生理作用
Prostaglandin E receptor 3 (PTGER3) serves as a receptor for prostaglandin (PG) E1 and E2, to carry out a number of physiological processes. PTGER3 specifically functions to reduce adenylyl cyclase action. It is involved in the activation of the Ras signaling pathway.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury
Han, X, et al.
Journal of Cerebral Blood Flow and Metabolism, 36(6), 1059-1074 (2016)
Tuberin Regulates Prostaglandin Receptor-Mediated Viability, via Rheb, in mTORC1-Hyperactive Cells
Li C, et al.
Molecular Cancer Research (2017)
The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE 2-and retaining PGE 1-mediated signaling in live cells
Akasaka H
Archives of Biochemistry and Biophysics, 616, 20-29 (2017)
Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival.
Ragnarsson G
British Journal of Cancer, 79(9-10), 1468-1474 (1999)
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