推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 102 kDa
种属反应性
mouse, human, rat
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GRM7(2917)
一般描述
Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
MGLUR7 (glutamate metabotropic receptor 7) is coded by the glutamate receptor, metabotropic 7 (GRM7) gene. It is expressed in several parts of the central nervous system. mGluR7 is located in the presynaptic zone of the synaptic cleft of glutamatergic synapses. GRM7 gene is mapped to human chromosome 3p26. Anti-MGLUR7 Antibody detects endogenous levels of total MGLUR7 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human mGluR7.
Immunogen Range: 866-915
Immunogen Range: 866-915
生化/生理作用
The gene coding MGLUR7 (glutamate metabotropic receptor 7) is associated with autism. GRM7 participates in the initiation of glutamate receptor. It also participates in schizophrenia and bipolar disorder.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Glutamate receptor, metabotropic 7 (GRM7) gene variations and susceptibility to autism: A case-control study.
Noroozi R, et al.
Autism Research : Official Journal of the International Society for Autism Research, 9(11), 1161-1168 (2016)
Hemizygous deletion on chromosome 3p26. 1 is associated with heavy smoking among African American subjects in the COPDGene Study.
Begum F, et al.
PLoS ONE, 11(10), e0164134-e0164134 (2016)
A polymorphism of the metabotropic glutamate receptor mGluR7 (GRM7) gene is associated with schizophrenia.
Ohtsuki T, et al.
Schizophrenia Research, 101(1-3), 9-16 (2008)
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