生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 337 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:40000
immunofluorescence: 1:100-1:500
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... LAMA1(284217)
一般描述
Anti-LAMA1 Antibody detects endogenous levels of total LAMA1 protein.
Laminins are extracellular matrix proteins. The LAMA1 (laminin subunit α 1) gene is mapped to chromosome 18p11.
免疫原
The antiserum was produced against synthesized peptide derived from human LAMA1.
Immunogen Range: 2501-2550
Immunogen Range: 2501-2550
应用
Anti-LAMA1, C-Terminal antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
LAMA1 (laminin subunit α 1) participates in several diseases like cancer, infections, inflammatory diseases and autoimmune disorders. Mutations in LAMA1 result in cerebellar dysplasia and cysts with and without retinal dystrophy. LAMA1 is also essential in the assembly of basement membrane and early growth of embryo.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Vertebrate evolution by interspecific hybridisation--are we polyploid?
Febs Letters, 400, 2-8 (1997)
Autoimmunity against laminins
Clinical Immunology (Orlando, Fla.), 170, 39-52 (2016)
Mutations in LAMA1 cause cerebellar dysplasia and cysts with and without retinal dystrophy
American Journal of Human Genetics, 95, 227-234 (2014)
?3 Chains of type V collagen regulate breast tumour growth via glypican-1
Nature Communications, 8 (2017)
Nature communications, 8, 14351-14351 (2017-01-20)
Pericellular α3(V) collagen can affect the functioning of cells, such as adipocytes and pancreatic β cells. Here we show that α3(V) chains are an abundant product of normal mammary gland basal cells, and that α3(V) ablation in a mouse mammary
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