SAB4500974
Anti-Fibronectin Antibody
rabbit polyclonal
别名:
CIG, FINC, 冷不溶性球蛋白, 纤连蛋白, 纤连蛋白1
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选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
rat, mouse, human
Citations:
19
Technique(s):
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Uniprot accession no.:
产品名称
抗-纤连蛋白1 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 262 kDa
species reactivity
rat, mouse, human
concentration
~1 mg/mL
technique(s)
ELISA: 1:1000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... FN1(2335)
Biochem/physiol Actions
纤连蛋白可参与细胞黏附、生长、迁移、伤口愈合、凝血和转移。FN1基因突变可导致肾小球病变。它在细胞附着和扩散、细胞骨架控制、细胞形态和分化等方面发挥着重要作用。FN1还参与细胞外基质的形成、止血和血栓形成。
Disclaimer
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Features and Benefits
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General description
抗-纤连蛋白1抗体检测内源性总纤连蛋白1蛋白水平。
纤连蛋白1是由FN1基因编码的细胞外基质糖蛋白。它在血浆和细胞表面表达。它位于人染色体3q35。
Immunogen
制备用于抗人纤连蛋白1合成肽的抗血清。
免疫原范围： 2337-2386
免疫原范围： 2337-2386
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Kusuma Suphakhong et al.
The Journal of biological chemistry, 298(11), 102554-102554 (2022-10-03)
N6-methyladenosine (m6A) is the most common internal chemical modification of mRNAs involved in many pathological processes including various cancers. In this study, we investigated the m6A-dependent regulation of JUN and JUNB transcription factors (TFs) during transforming growth factor-beta-induced epithelial-mesenchymal transition
Colorectal Cancer Aggressiveness is Related to Fibronectin Over Expression, Driving the Activation of SDF-1:CXC
Fernandes SG, et al.
International Journal of Cancer and Clinical Research, 3(8), 72-81 (2016)
Minoru Terashima et al.
The Journal of biological chemistry, 293(47), 18016-18030 (2018-09-29)
Long noncoding RNAs (lncRNAs) are important regulatory molecules in various biological and pathological processes, including cancer development. We have previously shown that the MEG3 lncRNA plays an essential role in transforming growth factor-β (TGF-β)-induced epithelial-mesenchymal transition (EMT) of human lung
Ziying Jian et al.
Cellular and molecular gastroenterology and hepatology, 6(4), 429-449 (2018-09-28)
Although nearly half of pancreatic ductal adenocarcinoma (PDAC) patients have diabetes mellitus with episodes of hyperglycemia, its tumor microenvironment is hypoglycemic. Thus, it is crucial for PDAC cells to develop adaptive mechanisms dealing with oscillating glucose levels. So far, the
Epigenetic regulation of epithelial-mesenchymal transition by KDM6A histone demethylase in lung cancer cells
Terashima M, et al.
Biochemical and Biophysical Research Communications, 490(4), 1407-1413 (2017)
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