产品名称
抗-肾上腺素受体 α-2A 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 48 kDa
species reactivity
mouse, human, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ADRA2A(150)
Biochem/physiol Actions
ADRA2A（α-2A 肾上腺素能受体基因）在易怒、冲动、攻击性和记忆性特征中起重要作用。ADRA2A 的突变影响胰岛素的释放和葡萄糖的调节。ADRA2A 的变异与较差的临床预后有关。它参与自闭症谱系障碍（ASD）。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
Features and Benefits
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General description
ADRA2A（α-2A 肾上腺素受体基因）位于人类染色体 10q25 上。它在尾状核中表达。
抗-肾上腺素受体α-2A 抗体可检测总肾上腺素受体-2A 蛋白的内源水平。
Immunogen
该抗血清是针对衍生自人肾上腺素能受体 α-2A 的合成肽制备的。
免疫原范围： 331-380
免疫原范围： 331-380
Physical form
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Alpha2A adrenergic receptor genetic variation contributes to hyperglycemia after myocardial infarction
Adefurin A, et al.
International Journal of Cardiology, 215, 482-486 (2016)
Abhishek Tripathi et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(13), E1659-E1668 (2015-03-17)
Recent evidence suggests that chemokine (C-X-C motif) receptor 4 (CXCR4) contributes to the regulation of blood pressure through interactions with α1-adrenergic receptors (ARs) in vascular smooth muscle. The underlying molecular mechanisms, however, are unknown. Using proximity ligation assays to visualize
Association between the adrenergic alpha 2A receptor gene (ADRA2A) and measures of irritability, hostility, impulsivity and memory in normal subjects
Comings DE, et al.
Psychiatric Genetics, 10(1), 39-42 (2000)
ADRA2A Germline Gene Polymorphism is Associated to the Severity, but not to the Risk, of Breast Cancer
Kaabi B, et al.
Pathology Oncology Research, 22(2), 357-365 (2016)
Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans
Ramos E, et al.
Diabetologia, 54(4), 783-788 (2011)
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