推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 48 kDa
种属反应性
mouse, human, rat
浓度
~1 mg/mL
1 of 4
此商品 | SAB4500566 | SAB4500576 | SAB4500578 |
|---|---|---|---|
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| biological source rabbit | biological source rabbit | biological source rabbit | biological source rabbit |
| antibody form affinity isolated antibody | antibody form affinity isolated antibody | antibody form affinity isolated antibody | antibody form affinity isolated antibody |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| species reactivity mouse, human, rat | species reactivity human, rat, mouse | species reactivity human | species reactivity human |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
一般描述
ADRA2A（α-2A 肾上腺素受体基因）位于人类染色体 10q25 上。它在尾状核中表达。
抗-肾上腺素受体α-2A 抗体可检测总肾上腺素受体-2A 蛋白的内源水平。
免疫原
该抗血清是针对衍生自人肾上腺素能受体 α-2A 的合成肽制备的。
免疫原范围： 331-380
免疫原范围： 331-380
生化/生理作用
ADRA2A（α-2A 肾上腺素能受体基因）在易怒、冲动、攻击性和记忆性特征中起重要作用。ADRA2A 的突变影响胰岛素的释放和葡萄糖的调节。ADRA2A 的变异与较差的临床预后有关。它参与自闭症谱系障碍（ASD）。
特点和优势
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
外形
兔IgG，溶于磷酸盐缓冲液（不含Mg2+和Ca2+），pH 7.4,150mM NaCl，0.02％叠氮化钠和50％甘油中。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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Diabetologia, 54(4), 783-788 (2011)
Alpha2A adrenergic receptor genetic variation contributes to hyperglycemia after myocardial infarction
Adefurin A, et al.
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Abhishek Tripathi et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(13), E1659-E1668 (2015-03-17)
Recent evidence suggests that chemokine (C-X-C motif) receptor 4 (CXCR4) contributes to the regulation of blood pressure through interactions with α1-adrenergic receptors (ARs) in vascular smooth muscle. The underlying molecular mechanisms, however, are unknown. Using proximity ligation assays to visualize
ADRA2A Germline Gene Polymorphism is Associated to the Severity, but not to the Risk, of Breast Cancer
Kaabi B, et al.
Pathology Oncology Research, 22(2), 357-365 (2016)
Ute A Schwinghammer et al.
Cells, 9(2) (2020-02-23)
The noradrenergic system is proposed to play a prominent role in the pathogenesis of liver fibrosis. While α1- and β-adrenergic receptors (ARs) are suggested to be involved in a multitude of profibrogenic actions, little is known about α2-AR-mediated effects and
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