推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 50 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:5000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CRHR1(1394)
一般描述
Anti-CRHR1 Antibody detects endogenous levels of total CRHR1 protein.
CRHR1 (corticotropin releasing factor receptor 1) is a member of the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. It has 13 exons and located on human chromosome 17q12-q22.
免疫原
The antiserum was produced against synthesized peptide derived from human CRHR1.
Immunogen Range: 75-124
Immunogen Range: 75-124
应用
Anti-CRHR1 antibody has been used in immunoprecipitation and western blotting.
生化/生理作用
CRHR1 (corticotropin releasing factor receptor 1) blocks the multiplication of endocrine-related cancer cell lines. It helps to initiate signal transduction pathways, that controls various functions like stress, reproduction, immune response and obesity.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Urocortinergic system in the testes of normal and cryptorchid dogs
Squillacioti C, et al.
Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft, 207, 91-96 (2016)
Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African-American Youths
Chen YF and Brody GH
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine, 57(2), 235-240 (2015)
Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
Yang G, et al.
Molecular Medicine Reports, 12(2), 2539-2546 (2015)
Chuting Li et al.
Neural plasticity, 2016, 5249893-5249893 (2016-03-01)
Several types of microRNA (miRNA) overexpression in the brain are associated with stress. One of the targets of miR-34c is the stress-related corticotrophin releasing factor receptor 1 mRNA (CRFR1 mRNA). Here we will probe into the short-term effect and long-term
Urocortin protects chondrocytes from NO-induced apoptosis: a future therapy for osteoarthritis?
Intekhab-Alam NY, et al.
Cell Death & Disease (2013)
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