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安全信息

SAB4301578

Sigma-Aldrich

抗 磷酸化 ERK1/2 (pThr 202/Tyr204 ) 兔抗

affinity isolated antibody

别名:

ERK-1, ERK1, ERT2, P44ERK1, PRKM3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

42 kDa
44 kDa

种属反应性

rat, mouse, human

浓度

1.0 mg/mL

技术

western blot: 1:500-1:1000 (Cell Lysate)

同位素/亚型

IgG

登记号

NP_001035145.1 

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pThr202/pTyr204)

基因信息

human ... MAPK3(5595)

特异性

抗体只有在苏氨酸 202 和酪氨酸 204磷酸化时检测内源性 p44/42 MAP 激酶水平。

免疫原

来源于人 p44/42 MAP 激酶的苏氨酸 202/酪氨酸 204 (F-L-T (p)-E-Y (p)-V-A) 磷酸化位点附近的肽序列。

特点和优势

完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多。

外形

溶于1.0mg/mL磷酸盐缓冲盐水(不含Mg2+和Ca2+),pH 7.4,含150mM NaCl、0.02%叠氮化钠和50%甘油。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Varun Kumar et al.
Current eye research, 46(5), 710-718 (2020-10-28)
Understanding molecular changes is essential for designing effective treatments for nonarteritic anterior ischemic optic neuropathy (AION), the most common acute optic neuropathy in adults older than 50 years. We investigated changes in the mitogen-activated protein kinase (MAPK) pathway after experimental AION
Lenka Halova et al.
Open biology, 11(4), 200405-200405 (2021-04-08)
Fluctuations in TOR, AMPK and MAP-kinase signalling maintain cellular homeostasis and coordinate growth and division with environmental context. We have applied quantitative, SILAC mass spectrometry to map TOR and nutrient-controlled signalling in the fission yeast Schizosaccharomyces pombe. Phosphorylation levels at
Vittorio Perfetti et al.
Oncotarget, 8(34), 56158-56167 (2017-09-17)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. GISTs express the receptor tyrosine kinase KIT, and the majority of GISTs present KIT gain-of-function mutations that cluster in the 5' end of the receptor juxtamembrane
Ravinder K Goyal et al.
BMC genomics, 19(1), 178-178 (2018-03-07)
The mitogen-activated protein kinase (MAPK) family is involved in signal transduction networks that underpin many different biological processes in plants, ranging from development to biotic and abiotic stress responses. To date this class of enzymes has received little attention in
Guangchao Zhao et al.
Rejuvenation research, 22(4), 325-334 (2018-11-10)
It is known that preconditional treatment with volatile anesthetics can induce tolerance of the brain to stroke. A previous study demonstrated that the involvement of TREK-1, a two-pore domain K+ channel, in sevoflurane preconditioning induced neuroprotection against focal cerebral ischemia

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