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Merck
CN
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安全信息

SAB3500141

Sigma-Aldrich

Anti-TRESK antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

Anti-KCNK18, Anti-Potassium channel subfamily K member 18, Anti-TRESK2, Anti-TRIK

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

human, rat, mouse

技术

immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... KCNK18(338567)

一般描述

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK is part of the potassium channel family. It is expressed in trigeminal and dorsal root ganglions. The protein is activated by calcium signals. The TRESK gene is localized on human chromosome 10q25.3.

免疫原

TRESK antibody was raised against a 17 amino acid peptide from near the center of human TRESK.

生化/生理作用

Potassium two pore domain channel subfamily K member 18 (KCNK18) or TRESK contributes to background K+ currents in sensory neurons. Mutations in the gene encoding it have been associated with familial migraine with aura.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500141.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Involvement of gap junction channels in the pathophysiology of migraine with aura
Denis Sarrouilhe
Frontiers in Physiology (2014)
KCNK18 (TRESK) genetic variants in Italian patients with migraine.
Rainero I
Headache (2014)
Identification of novel small molecule modulators of K2P18.1 two-pore potassium channel.
Bruner JK
European Journal of Pharmacology (2014)
TRESK: the lone ranger of two-pore domain potassium channels.
Enyedi P
Molecular and Cellular Endocrinology (2012)

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