SAB2702243
单克隆抗 5-甲基胞嘧啶/5-mC 小鼠抗
clone GT4111, affinity isolated antibody
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
GT4111, monoclonal
Application:
dot blot
immunohistochemistry
methylated DNA immunoprecipitation (MeDIP)
immunohistochemistry
methylated DNA immunoprecipitation (MeDIP)
Technique(s):
dot blot: suitable
immunohistochemistry: suitable
methylated DNA immunoprecipitation (MeDIP): suitable
immunohistochemistry: suitable
methylated DNA immunoprecipitation (MeDIP): suitable
Citations:
6
产品名称
单克隆抗 5-甲基胞嘧啶/5-mC 小鼠抗, clone GT4111, affinity isolated antibody
biological source
mouse
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
GT4111, monoclonal
form
buffered aqueous solution
concentration
1mg/mL
technique(s)
dot blot: suitable
immunohistochemistry: suitable
methylated DNA immunoprecipitation (MeDIP): suitable
isotype
IgG1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Application
建议的起始稀释度如下：Dot：检测依赖性稀释，EM：测定依赖性稀释，IHC-P：1:100-1:1000，IHC-Wm：1:50-1:500，MeDIP：测定依赖性稀释。尚未在其他应用中进行测试。最佳工作稀释液应由终端用户通过实验确定。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Features and Benefits
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多。
Immunogen
用于生成该抗体的免疫原对应 5-甲基胞嘧啶/5-mC。
Other Notes
纯化：由蛋白G亲和纯化
Physical form
磷酸盐缓冲液，未加保护剂。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Sunwang Xu et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 11(16), e2308531-e2308531 (2024-02-21)
Gallbladder cancer (GBC) is an extremely lethal malignancy with aggressive behaviors, including liver or distant metastasis; however, the underlying mechanisms driving the metastasis of GBC remain poorly understood. In this study, it is found that DNA methyltransferase DNMT3A is highly
Cen Jiang et al.
Cell death discovery, 8(1), 46-46 (2022-02-04)
The morbidity of papillary thyroid cancer (PTC) is on the rise, but its pathogenesis is still poorly understood. NR4A1 is a transcription factor primarily involving a wide range of pathophysiological responses, but its relationship with PTC malignancy remains unclear. This
Gerhard P Aigner et al.
Toxics, 10(2) (2022-02-25)
Earthworms are well-established model organisms for testing the effects of heavy metal pollution. How DNA methylation affects cadmium (Cd) detoxification processes such as the expression of metallothionein 2 (MT2), however, is largely unknown. We therefore exposed Lumbricus terrestris to 200
Manthan Patel et al.
BMC genetics, 21(1), 84-84 (2020-07-31)
The human CGGBP1 binds to GC-rich regions and interspersed repeats, maintains homeostasis of stochastic cytosine methylation and determines DNA-binding of CTCF. Interdependence between regulation of cytosine methylation and CTCF occupancy by CGGBP1 remains unknown. By analyzing methylated DNA-sequencing data obtained
Epigenetic activation of the elongator complex sensitizes gallbladder cancer to gemcitabine therapy.
Sunwang Xu et al.
Journal of experimental & clinical cancer research : CR, 40(1), 373-373 (2021-11-27)
Gallbladder cancer (GBC) is known for its high malignancy and multidrug resistance. Previously, we uncovered that impaired integrity and stability of the elongator complex leads to GBC chemotherapy resistance, but whether its restoration can be an efficient therapeutic strategy for
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