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Merck
CN

N6505

Sigma-Aldrich

β-烟酰胺腺嘌呤二核苷酸2′-磷酸,还原型 四钠盐 水合物

≥95% (HPLC)

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别名:
β-NADPH, 2′-NADPH 水合物, NADPH Na 4, TPNH2 Na4, 磷酸二氢烟酰胺腺嘌呤二核苷酸 四钠盐, 还原型三磷酸吡啶核苷酸 四钠盐, 还原型辅酶 II 四钠盐
经验公式(希尔记法):
C21H26N7Na4O17P3 · xH2O
CAS号:
分子量:
833.35 (anhydrous basis)
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51

质量水平

检测方案

≥95% (HPLC)
≥95% (spectrophotometric assay)

形式

powder

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1

InChI key

WYWWVJHQDVCHKF-MPUNMZHWSA-J

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应用

β-烟酰胺腺嘌呤二核苷酸2′-磷酸盐(NADP+)和β-烟酰胺腺嘌呤二核苷酸2′-磷酸还原酶(NADP)包含辅酶氧化还原对(NADP+:NADP),参与多种酶催化氧化还原反应。NADP+/NADPH氧化还原对促进合成代谢反应中的电子转移,如脂质和胆固醇生物合成和脂肪酰基链延长。NADP+/NADPH氧化还原对用于各种抗氧化机制,在这些机制中,它防止活性氧化物质的积累。NADPH是由戊糖磷酸途径(PPP)在体内产生。

生化/生理作用

NADPH是许多氧化还原酶(包括一氧化氮合成酶)的电子供体和辅助因子。

制备说明

酶促还原。

其他说明

根据固体重量包装。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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