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生化/生理作用
NS3 (nonstructural 3) proteinase is a non-structural protein, which is involved in the proteolytic processing of other non-structural proteins. T-cells which are specific towards the NS3 are crucial for regulating viremia.
其他说明
HCV NS3 antigen [1450-1643]-poly-Histidine-tagged
外形
Solution in 8 M urea, 20 mM Tris-HCl, pH 8.0, and 200 mM imidazole.
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
P Martin et al.
Journal of medical virology, 74(3), 397-405 (2004-09-16)
Interferon-gamma (IFN gamma)-producing CD8+ T cells have been shown to play a key role in the control or eradication of hepatitis C virus (HCV) infections. In particular, T cells specific of the non-structural protein 3 (NS3) are often associated with
R A Love et al.
Cell, 87(2), 331-342 (1996-10-18)
During replication of hepatitis C virus (HCV), the final steps of polyprotein processing are performed by a viral proteinase located in the N-terminal one-third of nonstructural protein 3. The structure of NS3 proteinase from HCV BK strain was determined by
Mangiferin induces radiosensitization in glioblastoma cells by inhibiting nonhomologous end joining.
Faguang Mu et al.
Oncology reports, 40(6), 3663-3673 (2018-10-03)
Although surgery and high‑dose radiotherapy have been the standard treatments for glioblastoma multiforme (GBM), these therapies are palliative, due to the high risk of local relapse. Emerging evidence has demonstrated that DNA double‑strand break (DSB) repair serves a critical role
Wenjing He et al.
Oncology letters, 17(1), 1008-1018 (2019-01-19)
Ovarian cancer is the most malignant gynecologic neoplasm in women and has the worst prognosis of all cancer types in women based on the 5-year survival rates. A previous study indicated that mangiferin exerts an anti-neoplastic effect on human ovarian
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