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H0879

溴化已烷双胺

Name: 溴化已烷双胺
Brand: SIGMA

nAChR antagonist

别名:

N,N,N,N′,N′,N′-六甲基六亚甲基二溴铵, 己烷-1,6-双（三甲基溴化铵）

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关于此项目

线性分子式:

(CH₃)₃N(Br)(CH₂)₆N(Br)(CH₃)₃

化学文摘社编号:

55-97-0

分子量:

362.19

NACRES:

NA.77

PubChem Substance ID:

24278459

UNSPSC Code:

12352200

EC Number:

200-249-7

MDL number:

MFCD00011787

Beilstein/REAXYS Number:

3715749

Quality level:

200

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属性

产品名称

溴化已烷双胺,

Quality Level

200

mp

282-285 °C (dec.)

SMILES string

[Br-].[Br-].C[N+](C)(C)CCCCCC[N+](C)(C)C

InChI

1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

InChI key

FAPSXSAPXXJTOU-UHFFFAOYSA-L

Gene Information

human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

说明

Application

溴化六甲铵已用于：

作为自主神经节阻断剂，研究其对大鼠胡须运动的影响
作为烟碱受体拮抗剂，研究其对小鼠抗原诱导关节炎(AIA)进展的影响
作为非选择性神经节烟碱型乙酰胆碱受体(nAChR)拮抗剂，研究其对小鼠中金雀花碱诱导的自主心血管反应的影响

Biochem/physiol Actions

溴化六甲铵是针对烟碱型乙酰胆碱受体(nAChR)的拮抗剂。它优先阻断自主神经节上的烟碱受体，只有在高剂量时才能穿过血脑屏障。

Features and Benefits

该化合物在《受体分类和信号转导手册》的乙酰胆碱受体（烟酸）页面上有详细描述。想要浏览手册的其他页面，请单击此处。

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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

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全球贸易项目编号

货号	GTIN
H0879-5G	04061833663523
H0879-100G	04061833663509
H0879-25G	04061833663516